Accèder directement au contenu

Hot of the press

* Nov2022 :
Le Monde "french main newspaper" The Assises des Mathématiques will be held from November 14 to 16 at UNESCO House. Explore the section :
Mathematics interacts with Biology

* May 2022 :
Le Monde "french main newspaper"
Les promesses de l’électroencéphalographie appliquée à l’anesthésie pour ajuster le niveau de sédation
"Une équipe française développe des algorithmes d’analyse en temps réel des données de l’EEG, pendant que le patient est sédaté, pour mieux prévenir le risque de surdosage de l’agent anesthésique."

* November 2021 :
 Kanishka Basnayake receives an honorary prize from C’Nano France for his PhD thesis work. Congratulations !

  Russian news about our recent collaborative work.

October 2021 :
Press release from CNRS about our recent work in the Science Advances on neuronal synaptic architechture that sustains nanophysiology [read more, in french] from Architecture de la mémoire et de l’apprentissage

image credit : F. Mannoulian

"L’architecture des neurones et des connections synaptiques soutient des fonctions cérébrales fondamentales comme l’acquisition et la modulation de la mémoire. .... En combinant théorie, modélisation mathématique et méthodes expérimentales, les scientifiques ont montré que le positionnement d’acteurs moléculaires à l’échelle nanométrique est stratégique pour le contrôle d’événements calciques qui permettent de programmer les neurones sur le long terme....."

image credit : F. Mannoulian
see also [Basnayake et al.]

April 2020 :
 D. Holcman has received the "pre-maturation" CNRS award for his work on predicting anesthesia using modeling-machine-learning.

March 2020 :
 D. Holcman has been laureat of the ERC-Advanced grant 2020.PSL press released CNRS-press release.

Dec 2019 :
French Magazine "Pour La science"explains our approach about analyzing EEG to insure a better anesthesia.

Sept 2019 : Press release from CNRS about our publication on using IA to predict the depth of anesthesia

June 2019 : : Understanding Memory following our paper published in PLoS Biology, press advertisement :

Jan 2018 :
Our sperm paper got 2018 Pineapple Science Award (Math Prize), which is a chinese version of Ig Noble Prize.

The ceremony was in Hangzhou, China :

May 2017

The narrow escape theory has inspired the FARGO TV series

Jan 2015 : K. Dao duc received the Pierre-Gilles Degenne Prize for his PhD thesis. More to read..

June 2014 : D. Holcman became member, as an overseas Fellow, of the Churchill College, Cambridge, UK.

May 2014 Survey and Review :

The Survey and Review article in this issue is “The Narrow Escape Problem,” by D. Holcman and Z. Schuss. Read More :
"This article will be a valuable resource for readers with interests at the interface between probability theory and partial differential equations, and those who study asymptotic analysis of singular perturbation problems and applications to physics, biochemistry, and neuroscience.

April 2014 : Nature Reviews Neuroscience
Research Highlight

Synaptic transmission : Invasion of the astrocytes !
...Moreover, in a computational synapse model, an astroglial process invading a synapse by 150 nm reduced AMPA receptor currents by 50% and doubled GLT currents (compared with a synapse without astroglial invasion), suggesting that extension of astroglial processes into synapses indeed reduces excitatory transmission...More to read

December 2013 : Phys. Rev. Letter

Physics Viewpoint : A model based on statistical mechanics is applied to describe a key factor determining the senescence of biological cells.

"We may think of built-in obsolescence as a modern marketing trick, but biology got there first. Rather than being able to replicate indefinitely, most cells in our bodies divide only a finite number of times before they switch off. The aging of a cell (senescence) is the process of accumulative changes to its molecular structure that disrupt its function with time, leading to its degradation and death. A key factor in senescence is the shortening of the protective ends of a cell’s chromosomes, called telomeres. As reported in Physical Review Letters [1], Khanh Dao Duc and David Holcman at Ecole Normale Supérieure, France, have formulated a statistical mechanics model that describes how this process is regulated, providing a powerful method for predicting whether cells live or die....."

September 2012 :

Voir comprendre et quantifier les cellules en action

June 2011 :

Interview with
Impact of the Narrow escape theory:Alexei Cheviakov and Michael Ward talk with and answer a few questions about this month’s Fast Breaking Paper in the field of be read.

May 2010

Interview with the CNRS journal : Jeunes Chercheurs : "When biology becomes mathematics..."

Oct 2008

ERC press release : "ERC starting grant winners set out their plans in"
"The first winners of the ERC (European Research Council) starting grant explained how they planned to use their funding and gave their opinions on the workings of the ERC at a meeting in Paris, France, on 7 October."

More information about the Open day 7 Oct 2008 :

Nov 2004

Chaire d’excellence 2004-2007
"Dans un contexte de forte compétition internationale, les chercheurs de haut niveau sont les cibles de toutes les
convoitises parce qu’ils ont entre les mains les clés de l’avenir et de la croissance. La France se mobilise et se
donne les moyens de les accueillir pour développer leurs projets de recherche au travers du programme
« Chaires d’excellence ».
Parce que la fuite des cerveaux n’est pas une fatalité et que la recherche française est réputée pour son
excellence, 15 chercheurs de haut niveau vont venir ou revenir travailler en France."

Read more in http://wwww.enseignementsup-recherc...