Collaborations

Suzanne Marques (équipe Meyer) — 2015-03-18T12:09:13Z

Equipes collaboratrices

Linda Sperling (CGM, Gif-sur-Yvette, France) voir
Sandra Duharcourt (IJM, Paris, France) voir
Mireille Bétermier (CGM, Gif-sur-Yvette, France) voir
Laurent Duret (LBBE, UCB Lyon 1, Lyon, France) voir
Hadi Quesneville (INRA, Versailles, France) voir
Jean-Marc Aury/Karine Labadie (Génoscope, Evry, France)
Ewa Przybòs, (ISEA PAS, Cracovie, Pologne)
Alexey Potekhin (SPBU, St. Petersbourg, Russie)
Mariusz Nowacki (IZB, Université de Berne, Suisse) voir

La recherche sur les ciliés

Paramecium : Parameciumdb
Tetrahymena : genome database
Oxytricha : Oxytricha genome projects

Publications

Suzanne Marques (équipe Meyer) — 2015-02-09T11:39:55Z

2011 - 2018

Bhullar S, Denby Wilkes C, Arnaiz O, Nowacki M, Sperling L, Meyer E. A mating-type mutagenesis screen identifies a zinc-finger protein required for specific DNA excision events in Paramecium. Nucleic Acids Res. 2018 ; 46(18) : 9550–9562. doi:10.1093/nar/gky772.

Orias E, Singh DP, Meyer E. Genetics and epigenetics of mating type determination in Paramecium and Tetrahymena. Annu Rev Microbiol. 2017 ; 71:133-156. doi:10.1146/annurev-micro-090816-093342.

Guérin F, Arnaiz O, Boggetto N, Denby Wilkes C, Meyer E, Sperling L, Duharcourt S. Flow-cytometry sorting of nuclei enables the first global characterization of Paramecium germline DNA and transposable elements. BMC Genomics. 2017 ; 18(1):327. doi : 10.1186/s12864-017-3713-7.

Saudemont B, Popa A, Parmley JL, Rocher V, Blugeon C, Necsulea A, Meyer E, Duret L. The fitness cost of mis-splicing is the main determinant of alternative splicing patterns. Genome Biol. 2017 ; 18(1):208. doi:10.1186/s13059-017-1344-6.

Carradec Q, Götz U, Arnaiz O, Pouch J, Simon M, Meyer E, et al. Primary and secondary siRNA synthesis triggered by RNAs from food bacteria in the ciliate Paramecium tetraurelia. Nucleic Acids Res 2015. doi:10.1093/nar/gku1331. /pdf

Marmignon A, Bischerour J, Silve A, Fojcik C, Dubois E, Arnaiz O, et al. Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Ciliate Paramecium tetraurelia. PLoS Genetics 2014 ; 10:e1004552. doi:10.1371/journal.pgen.1004552. /pdf

Marker S, Carradec Q, Tanty V, Arnaiz O, Meyer E. A forward genetic screen reveals essential and non-essential RNAi factors in Paramecium tetraurelia. Nucleic Acids Research 2014 ; 42:7268–80. doi:10.1093/nar/gku223. /pdf

Singh DP, Saudemont B, Guglielmi G, Arnaiz O, Goût J-F, Prajer M, et al. Genome-defence small RNAs exapted for epigenetic mating-type inheritance. Nature 2014 ; 509:447–52. doi:10.1038/nature13318. Selected by Faculty of 1000. /pdf

Chalker DL, Meyer E, Mochizuki K. Epigenetics of Ciliates. Cold Spring Harbor Perspectives in Biology 2013 ; 5:a017764–a017764. doi:10.1101/cshperspect.a017764. /pdf

Arnaiz O, Mathy N, Baudry C, Malinsky S, Aury J-M, Denby Wilkes C, et al. The Paramecium Germline Genome Provides a Niche for Intragenic Parasitic DNA : Evolutionary Dynamics of Internal Eliminated Sequences. PLoS Genetics 2012 ; 8:e1002984. doi:10.1371/journal.pgen.1002984. /pdf

Kapusta A, Matsuda A, Marmignon A, Ku M, Silve A, Meyer E, et al. Highly Precise and Developmentally Programmed Genome Assembly in Paramecium Requires Ligase IV–Dependent End Joining. PLoS Genet 2011 ; 7:e1002049.
doi:10.1371/journal.pgen.1002049. /pdf

Bouhouche K, Gout J-F, Kapusta A, Betermier M, Meyer E. Functional specialization of Piwi proteins in Paramecium tetraurelia from post-transcriptional gene silencing to genome remodelling. Nucleic Acids Research 2011 ;39:4249–64. doi:10.1093/nar/gkq1283. /pdf

2006 - 2010

Arnaiz O, Goût J-F, Bétermier M, Bouhouche K, Cohen J, Duret L, et al. Gene expression in a paleopolyploid : a transcriptome resource for the ciliate Paramecium tetraurelia. BMC Genomics 2010 ; 11:547. doi:10.1186/1471-2164-11-547. /pdf

Marker S, Mouël AL, Meyer E, Simon M. Distinct RNA-dependent RNA polymerases are required for RNAi triggered by double-stranded RNA versus truncated transgenes in Paramecium tetraurelia. Nucl Acids Res 2010 ; 38:4092–107. doi:10.1093/nar/gkq131. /pdf

Beisson J, Betermier M, Bre M-H, Cohen J, Duharcourt S, Duret L, et al. DNA Microinjection into the Macronucleus of Paramecium. Cold Spring Harbor Protocols 2010 ; 2010:pdb.prot5364 – pdb.prot5364. doi:10.1101/pdb.prot5364. /pdf

Baudry C, Malinsky S, Restituito M, Kapusta A, Rosa S, Meyer E, et al. PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements in the ciliate Paramecium tetraurelia. Genes & Development 2009 ; 23:2478–83. doi:10.1101/gad.547309. Selected by Faculty of 1000. /pdf

Duharcourt S, Lepère G, Meyer E. Developmental genome rearrangements in ciliates : a natural genomic subtraction mediated by non-coding transcripts. Trends in Genetics 2009 ; 25:344–50. doi:10.1016/j.tig.2009.05.007. /pdf

Lepere G, Nowacki M, Serrano V, Gout J-F, Guglielmi G, Duharcourt S, et al. Silencing-associated and meiosis-specific small RNA pathways in Paramecium tetraurelia. Nucleic Acids Research 2009 ; 37:903–15. doi:10.1093/nar/gkn1018. /pdf

Gratias A, Lepère G, Garnier O, Rosa S, Duharcourt S, Malinsky S, et al. Developmentally programmed DNA splicing in Paramecium reveals short-distance crosstalk between DNA cleavage sites. Nucleic Acids Res 2008 ; 36:3244–51.
doi:10.1093/nar/gkn154. /pdf

Lepere G, Betermier M, Meyer E, Duharcourt S. Maternal noncoding transcripts antagonize the targeting of DNA elimination by scanRNAs in Paramecium tetraurelia. Genes & Development 2008 ; 22:1501–12. doi:10.1101/gad.473008. /pdf

Duret L, Cohen J, Jubin C, Dessen P, Goût J-F, Mousset S, et al. Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia : A somatic view of the germline. Genome Res 2008 ; 18:585–96. doi:10.1101/gr.074534.107. /pdf

Jaillon O, Bouhouche K, Gout J-F, Aury J-M, Noel B, Saudemont B, et al. Translational control of intron splicing in eukaryotes. Nature 2008 ; 451:359–62.
doi:10.1038/nature06495. Selected by Faculty of 1000. /pdf

Meyer E, Chalker DL. Epigenetics of Ciliates. Cold Spring Harbor Laboratory Press 2007:pp. 127–50.

Aury J-M, Jaillon O, Duret L, Noel B, Jubin C, Porcel BM, et al. Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia. Nature 2006 ; 444:171–8. doi:10.1038/nature05230. Selected by Faculty of 1000. /pdf

2001 - 2005

Nowacki M, Zagorski-Ostoja W, Meyer E. Nowa1p and Nowa2p : Novel Putative RNA Binding Proteins Involved in trans-Nuclear Crosstalk in Paramecium tetraurelia. Current Biology 2005 ; 15:1616–28. doi:10.1016/j.cub.2005.07.033. /pdf

Meyer É, Beisson J. Épigénétique : la paramecia comme modèle d'étude. Médecine/sciences 2005 ; 21:377–83. doi:10.1051/medsci/2005214377. /pdf

Garnier O, Serrano V, Duharcourt S, Meyer E. RNA-Mediated Programming of Developmental Genome Rearrangements in Paramecium tetraurelia. Molecular and Cellular Biology 2004 ; 24:7370–9. doi:10.1128/MCB.24.17.7370-7379.2004. /pdf

Zagulski M, Nowak JK, Le Mouël A, Nowacki M, Migdalski A, Gromadka R, et al. High Coding Density on the Largest Paramecium tetraurelia Somatic Chromosome. Current Biology 2004 ; 14:1397–404. doi:10.1016/j.cub.2004.07.029. /pdf

Le Mouel A, Butler A, Caron F, Meyer E. Developmentally Regulated Chromosome Fragmentation Linked to Imprecise Elimination of Repeated Sequences in Paramecia. Eukaryotic Cell 2003 ; 2:1076–90. doi:10.1128/EC.2.5.1076-1090.2003. /pdf

Meyer E, Garnier O. 10 Non-mendelian inheritance and homology-dependent effects in ciliates. Advances in Genetics 2002 ;46:305–37. doi:10.1016/S0065-2660(02)46011-7. /pdf

Kervestin S, Garnier OA, Karamyshev AL, Ito K, Nakamura Y, Meyer E, et al. Isolation and expression of two genes encoding eukaryotic release factor 1 from Paramecium tetraurelia. J Eukaryot Microbiol 2002 ; 49:374–82. doi:10.1111/j.1550-7408.2002.tb00215.x. /pdf

Dessen P, Zagulski M, Gromadka R, Plattner H, Kissmehl R, Meyer E, et al. Paramecium genome survey : a pilot project. Trends in Genetics 2001 ; 17:306–8.
doi:10.1016/S0168-9525(01)02307-1. /pdf

1996 - 2000

Bétermier M, Duharcourt S, Seitz H, Meyer E. Timing of Developmentally Programmed Excision and Circularization of Paramecium Internal Eliminated Sequences. Mol Cell Biol 2000 ; 20:1553–61. doi:10.1128/MCB.20.5.1553-1561.2000. /pdf

Meyer E, Cohen J. Paramecium Molecular Genetics : Functional Complementation and Homology-Dependent Gene Inactivation. Protist 1999 ; 150:11–6. doi:10.1016/S1434-4610(99)70004-0. /pdf

Duharcourt S, Keller A-M, Meyer E. Homology-Dependent Maternal Inhibition of Developmental Excision of Internal Eliminated Sequences in Paramecium tetraurelia. Molecular and Cellular Biology 1998 ; 18:7075–85. /pdf

Meyer E, Butler A, Dubrana K, Duharcourt S, Caron F. Sequence-specific epigenetic effects of the maternal somatic genome on developmental rearrangements of the zygotic genome in Paramecium primaurelia. Mol Cell Biol 1997 ; 17:3589–99. /pdf

Meyer E, Duharcourt S. Epigenetic regulation of programmed genomic rearrangements in Paramecium aurelia. J Eukaryot Microbiol 1996 ; 43:453–61. /pdf

Meyer E, Duharcourt S. Epigenetic Programming of Developmental Genome Rearrangements in Ciliates. Cell 1996 ; 87:9–12. doi:10.1016/S0092-8674(00)81317-3. /pdf

Meyer E, Keller A-M. A Mendelian Mutation Affecting Mating-Type Determination Also Affects Developmental Genomic Rearrangements in Paramecium tetraurelita. Genetics 1996 ; 143:191–202. /pdf

Before 1995

Duharcourt S, Butler A, Meyer E. Epigenetic self-regulation of developmental excision of an internal eliminated sequence on Paramecium tetraurelia. Genes & Development 1995 ; 9:2065–77. doi:10.1101/gad.9.16.2065. /pdf

Keller AM, Le Mouël A, Caron F, Katinka M, Meyer E. The differential expression of the G surface antigen alleles in Paramecium primaurelia heterozygous cells correlates to macronuclear DNA rearrangement. Dev Genet 1992 ; 13:306–17. doi:10.1002/dvg.1020130408. /pdf

Meyer E. Induction of specific macronuclear developmental mutations by microinjection of a cloned telomeric gene in Paramecium primaurelia. Genes Dev 1992 ; 6:211–22. doi:10.1101/gad.6.2.211. /pdf

Caron F, Meyer E. Molecular Basis of Surface Antigen Variation in Paramecia. Annual Review of Microbiology 1989 ; 43:23–42. doi:10.1146/annurev.mi.43.100189.000323. /pdf

Prat A, Katinka M, Caron F, Meyer E. Nucleotide sequence of the Paramecium primaurelia G surface protein : A huge protein with a highly periodic structure. Journal of Molecular Biology 1986 ; 189:47–60. doi:10.1016/0022-2836(86)90380-3. /pdf

Meyer E, Caron F, Baroin A. Macronuclear structure of the G surface antigen gene of Paramecium primaurelia and direct expression of its repeated epitopes in Escherichia coli. Mol Cell Biol 1985 ; 5:2414–22. /pdf

Caron F, Meyer E. Does Paramecium primaurelia use a different genetic code in its macronucleus ? Nature 1985 ; 314:185–8. /pdf

Meyer E, Caron F, Guiard B. Blocking of in vitro translation of Paramecium messenger RNAs is due to messenger RNA primary structure. Biochimie 1984 ; 66:403–12.

Membres de l'équipe

Suzanne Marques (équipe Meyer) — 2014-10-01T06:46:36Z

Eric Meyer DR CNRS mail	Sophie Malinsky MC Paris 7 mail	Véronique Tanty IE INSERM mail
Guillaume Delevoye Doctorant mail	Cristina Engeroff Post-doc mail	Suzanne Marques Doctorante mail

IBENS - ENS