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Odelin G, Faure E, Coulpier F, Di Bonito M, Bajolle F, Studer M, Avierinos JF, Charnay P, Topilko P, Zaffran S. Krox20 defines a subpopulation of cardiac neural crest cells contributing to arterial valves and bicuspid aortic valve. Development. 2017 Nov 20. pii : dev.151944. Pubmed

Furlan A, Dyachuk V, Kastriti ME, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko PV, Ernfors P, Adameyko I. Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science. 2017 Jul 7 ;357(6346). pii : eaal3753. Pubmed

Thierion E, Le Men J, Collombet S, Hernandez C, Coulpier F, Torbey P, Thomas-Chollier M, Noordermeer D, Charnay P, Gilardi-Hebenstreit P. Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements. PLoS Genet. 2017 Jul 27 ;13(7):e1006903. Pubmed

Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, Ku M, Denli AM, Kerman BE, Charnay P, Kelsoe JR, Marchetto MC, Gage FH. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Jun 6 ;8(6):1757-1769. Pubmed

Stern S, Santos R, Marchetto MC, Mendes AP, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients’ responsiveness to lithium. Mol Psychiatry. 2017 Feb 28. doi : 10.1038/mp.2016.260. Pubmed


Wu XS, Lee SH, Sheng J, Zhang Z, Zhao WD, Wang D, Jin Y, Charnay P, Ervasti JM, Wu LG. Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses. Neuron. 2016 Dec 7 ;92(5):1020-1035. Pubmed

Jourdon A, Gresset A, Spassky N, Charnay P, Topilko P, Santos R. Prss56, a novel marker of adult neurogenesis in the mouse brain. Brain Struct Funct. 2016 Dec ;221(9):4411-4427. Pubmed

de Frutos CA, Bouvier G, Arai Y, Thion MS, Lokmane L, Keita M, Garcia-Dominguez M, Charnay P, Hirata T, Riethmacher D, Grove EA, Tissir F, Casado M, Pierani
A, Garel S. Reallocation of Olfactory Cajal-Retzius Cells Shapes Neocortex Architecture. Neuron. 2016 Oct 19 ;92(2):435-448. Pubmed


Grünewald TG, Bernard V, Gilardi-Hebenstreit P, Raynal V, Surdez D, Aynaud MM, Mirabeau O, Cidre-Aranaz F, Tirode F, Zaidi S, Perot G, Jonker AH, Lucchesi C, Le Deley MC, Oberlin O, Marec-Bérard P, Véron AS, Reynaud S, Lapouble E, Boeva V, Rio Frio T, Alonso J, Bhatia S, Pierron G, Cancel-Tassin G, Cussenot O, Cox DG, Morton LM, Machiela MJ, Chanock SJ, Charnay P, Delattre O. Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite. Nat Genet. 2015 Sep ;47(9):1073-8. Pubmed

Gresset A, Coulpier F, Gerschenfeld G, Jourdon A, Matesic G, Richard L, Vallat JM, Charnay P, Topilko P. Boundary Caps Give Rise to Neurogenic Stem Cells and Terminal Glia in the Skin. Stem Cell Reports. 2015 Aug 11 ;5(2):278-90. Pubmed

Labalette C, Wassef MA, Desmarquet-Trin Dinh C, Bouchoucha YX, Le Men J, Charnay P, Gilardi-Hebenstreit P. Molecular dissection of segment formation in the developing hindbrain.
Development. 2015 Jan 1 ;142(1):185-95. Pubmed


Odelin, G., Faure, E., Kober, F., Maurel-Zaffran, C., Théron, A., Coulpier, F., Guillet, B., Bernard, M., Avierinos, J.F., Charnay, P., Topilko P. and Zaffran, S. Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.
Cardiovasc Res. 2014 Dec 1 ;104(3):443-55.Pubmed

Jin, S., Kim, J., Willert, T., Klein-Rodewald, T., Garcia-Dominguez, M., Mosqueira, M., Fink, R., Esposito, I., Hofbauer, L.C., Charnay, P., Kieslinger, M. 
Nat Commun. 2014 May 2 ;5:3793. Pubmed


Bouchoucha YX, Reingruber J, Labalette C, Wassef MA, Thierion E, Desmarquet-Trin Dinh C, Holcman D, Gilardi-Hebenstreit P, Charnay P. Dissection of a Krox20 positive feedback loop driving cell fate choices in hindbrain patterning.
Mol Syst Biol. 2013 Sep 24 ;9:690. Pubmed

Iwasaki, Y., Fujio, K., Okamura, T., Yanai, A., Sumitomo, S., Shoda, H., Tamura, T., Yoshida, H., Charnay, P., and Yamamoto, K. Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells.
Eur J Immunol. 2013 Apr ;43(4):1063-73. Pubmed

Bouchoucha YX, Charnay P, Gilardi-Hebenstreit P. Ablation of Egr2-positive cells in male mouse anterior pituitary leads to atypical isolated GH deficiency.
Endocrinology. 2013 Jan ;154(1):270-82. Pubmed


Richard, L., Topilko, P., Magy, L., Decouvelaere, A.V., Charnay, P., Funalot, B. and Vallat, J.M. Endoneurial fibroblast-like cells.
J Neuropathol Exp Neurol. 2012 Nov ;71(11):938-47. Pubmed

Fröb, F, Bremer, M., Finzch, M., Kichko, T., Reeh, P., Tamm, E.R., Charnay, P. and Wegner, M. Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10.
Glia. 2012 May ;60(5):806-19. Pubmed

Funalot B, Topilko P, Arroyo MA, Sefiani A, Hedley-Whyte ET, Yoldi ME, Richard L, Touraille E, Laurichesse M, Khalifa E, Chauzeix J, Ouedraogo A, Cros D, Magdelaine C, Sturtz FG, Urtizberea JA, Charnay P, Bragado FG, Vallat JM. Homozygous deletion of an EGR2 enhancer in congenital amyelinating neuropathy.
Ann Neurol. 2012 May ;71(5):719-23 Pubmed

Apra C, Richard L, Coulpier F, Blugeon C, Gilardi-Hebenstreit P, Vallat JM, Lindner V, Charnay P, Decker L. Cthrc1 is a negative regulator of myelination in Schwann cells.
Glia. 2012 Mar ;60(3):393-403 Pubmed


Garcia-Gutiérrez, P., Juarez-Vicente, F., Gallardo-Chamizo, F., Charnay, P. and Garcia-Dominguez, M. The transcription factor Krox20 acts as a ligase for the sumoylation of its co-regulators, the Nab proteins.
EMBO Rep. 2011 Sep 30 ;12(10):1018-23. Pubmed

Zujovic V, Thibaud J, Bachelin C, Vidal M, Deboux C, Coulpier F, Stadler N, Charnay P, Topilko P, Baron-Van Evercooren A. Boundary cap cells are peripheral nervous system stem cells that can be redirected into central nervous system lineages.
Proc Natl Acad Sci U S A. 2011 Jun 28 ;108(26):10714-9 Pubmed

Blugeon, C., LeCrom, S., Charnay, P and Decker, L. Dok4 is involved in Schwann cell myelination and axonal interaction in vitro.
Glia. 2011 Mar ;59(3):351-62. Pubmed

Coulpier F, Decker L, Funalot B, Vallat JM, Garcia-Bragado F, Charnay P, Topilko P. Krox20 inactivation in the PNS leads to CNS/PNS boundary transgression by central glia.
Rev Neurol (Paris). 2011 Jan ;167(1):51-6 Pubmed

Labalette C, Bouchoucha YX, Wassef MA, Gongal PA, Le Men J, Becker T, Gilardi-Hebenstreit P, Charnay P. Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4.
Development. 2011 Jan ;138(2):317-26 Pubmed

Cifuentes-Diaz, C., Dubourg, O., Irinopoulou, T., Vigny, M., Lachkar, S., Decker, L., Charnay, P., Denisenko, N., Maisonobe, T., Léger, J.-M., Viala, K., Hauw, J.-J. and Girault, J.-A. Nodes of Ranvier and paranodes in chronic acquired neuropathies.
PLoS One. 2011 Jan 18 ;6(1):e14533. Pubmed


Coulpier F, Decker L, Funalot B, Vallat JM, Garcia-Bragado F, Charnay P, Topilko P, CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function.
The Journal of Neuroscience 2010, Apr 28 ;30(17):5958-67 PubMed

Zujovic V, Thibaud J, Bachelin C, Vidal M, Coulpier F, Charnay P, Topilko P, Baron-Van Evercooren A, Boundary cap cells are highly competitive for CNS remyelination : fast migration and efficient differentiation in PNS and CNS myelin-forming cells.
Stem Cells, 2010 Mar 31 ;28(3):470-9 PubMed

Esain V, Postlethwait JH, Charnay P, Ghislain J, FGF-receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9.
Development. 2010 Jan ;137(1):33-42. PubMed


Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P, Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers.
Glia. 2009 Oct ;57(13):1450-7. PubMed

Mayer SI, Rössler OG, Endo T, Charnay P, Thiel G, Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors.
J Cell Sci. 2009 Sep 15 ;122(Pt 18):3340-50. PubMed

Thoby-Brisson M, Karlén M, Wu N, Charnay P, Champagnat J, Fortin G, Genetic identification of an embryonic parafacial oscillator coupling to the preBötzinger complex.
Nat Neurosci. 2009 Aug ;12(8):1028-35. PubMed

Desmazières A, Charnay P, Gilardi-Hebenstreit P, Krox20 controls the transcription of its various targets in the developing hindbrain according to multiple modes.
J Biol Chem. 2009 Apr 17 ;284(16):10831-40. PubMed


Vázquez-Echeverría, C., Dominguez-Frutos, E., Schimmang, T., Charnay, P. and Pujades, C. Analysis of mouse kreisler mutants reveals new roles of hindbrain-derived FGFs in otic neurogenesis.
Dev Biol. Oct. 1 ; 322(1):167-178 PubMed

Poirier, R., Cheval, H., Mailhes, C., Garel, S., Charnay, P., Davis, S. and Laroche, S. Distinct functions of Egr gene family members in cognitive processes.
Front. Neurosci. *2*,1:47-55. doi:10.3389/neuro.01.002.2008.

Wassef MA, Chomette D, Pouilhe M, Stedman A, Havis E, Desmarquet-Trin Dinh C, Schneider-Maunoury S, Gilardi-Hebenstreit P, Charnay P, Ghislain J, Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.
Development 135, 3369-3378 PubMed

Desmazières A, Decker L, Vallat JM, Charnay P, Gilardi-Hebenstreit P. Disruption of Krox20-Nab interaction in the mouse leads to peripheral neuropathy with biphasic evolution.
J Neurosci. Jun 4 ;28(23):5891-900 PubMed

Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, Ibañez CF, Ernfors P, Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.
Nature 451, 7177 : 460-4 PubMed


Poirier, R., Cheval, H., Mailhes, C., Charnay, P., Davis, S. and Laroche, S. Paradoxical role of an Egr transcription factor family member, Egr2/Krox20, in learning and memory.
Front. Behav. Neurosci./ *1*:6. doi:10.3389/neuro.08.006.2007.

Pouilhe M, Gilardi-Hebenstreit P, Desmarquet-Trin Dinh C and Charnay P. Direct regulation of vHnf1 by retinoic acid signaling and MAF-related factors in the neural tube.
Dev Biol. Sep 15 ;309(2):344-357 PubMed

Chatonnet F, Wrobel LJ, Mezières-Robert V, Pasqualetti M, Ducret S, Taillebourg E, Charnay P, Rijli FM, Champagnat J, Distinct roles of Hoxa2 and Krox20 in the development of rhythmic neural networks controlling inspiratory depth, respiratory frequency, and jaw opening.
Neural development 2, 5792 : 19 PubMed


Oury F, Murakami Y, Renaud JS, Pasqualetti M, Charnay P, Ren SY, Rijli FM, Hoxa2- and rhombomere-dependent development of the mouse facial somatosensory map.
Science 313, 5792 : 1408-13 PubMed

Ghislain, J. and Charnay, P. Control of myelination in Schwann cells : a Krox20 cis-regulatory element integrates Oct6, Brn2 and Sox10 activities.
EMBO Reports, 7, 52-58. PubMed

Chomette, D., Frain, M., Cereghini, S., Charnay, P. and Ghislain, J. Krox20 hindbrain cis-regulatory landscape : interplay between multiple long-range initiation and autoregulatory elements.
Development, 133, 1253-1262. PubMed

Lopez-Bendito, G., Cautinat, A., Sanchez, J.A., Bielle, F., Flames, N., Charnay, P., Marin, O. and Garel, S. Tangential migration controls axon guidance : a role for neuregulin-1 in thalomocortiocal axon navigation.
Cell, 125(1):127-42 PubMed

Garcia-Dominguez, M., Gilardi-Hebenstreit, P. and Charnay, P. PIASxß acts as an activator of Hoxb1 expression and is antagonised by Krox20 during hindbrain segmentation.
EMBO J., Jun 7 ;25(11):2432-42. Pubmed

Vesque, C., Anselme, I., Couvé, E., Charnay, P. and Schneider-Maunoury, S. Cloning of vertebrate protogenin and comparative expression during axis elongation.
Dev. Dyn., Oct ;235(10):2836-44. Pubmed

Pezeron, G., Anselme, I., Laplante, M., Ellingsen, S., Becker, T.S., Rosa, F.M., Charnay, P., Schneider-Maunoury, S., Mourrain, P. and Ghislain, J. Duplicate sfrp1 genes in zebrafish : sfrp1a is dynamically expressed in the developing central nervous system, gut and lateral line.
Gene Expression Patterns, Oct ;6(8):835-42. Pubmed

Decker, L., Desmarquet, C., Taillebourg, E., Ghislain, J., Vallat J.-M. and Charnay, P. Peripheral myelin maintenance is a dynamic process requiring constant Krox20 expression.
J. Neuroscience, Sep 20 ;26(38):9771-9. PubMed