Publications
Wennagel D, Charrier C. Trans-synaptic functions of non-canonical ionotropic glutamate receptors in circuit wiring and plasticity (2025) Curr Opin Neurobiol. 93:103053. doi : 10.1016/j.conb.2025.103053.
Christopoulou E and Charrier C. Molecular mechanisms of the specialization of human synapses in the neocortex (2024). Curr Opin Genet Dev. 89:102258. doi : 10.1016/j.gde.2024.102258.
Assendorp N, Fossati M, Libé-Philippot B, Christopoulou E, Depp M, Rapone R, Dingli F, Loew D, Vanderhaeghen P, Charrier C. CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny (2024) Cell Reports. 43(10):114797. doi : 10.1016/j.celrep.2024.114797.
Libé-Philippot B, Iwata R, Recupero AJ, Wierda K, Bernal Garcia S, Hammond L, van Benthem A, Limame R, Ditkowska M, Beckers S, Gaspariunaite V, Peze-Heidsieck E, Remans D, Charrier C, Theys T, Polleux F, Vanderhaeghen P. Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition (2025) Neuron. 112(21):3602-3617.e9. doi : 10.1016/j.neuron.2024.08.021.
Piot L, Heroven C, Bossi S, Zamith J, Malinauskas T, Johnson C, Wennagel D, Stroebel D, Charrier C, Aricescu AR, Mony L, Paoletti P. GluD1 binds GABA and controls inhibitory plasticity (2023) Science. 382(6677):1389-1394. doi : 10.1126/science.adf3406.
Gemin O, Serna P, Zamith J, Assendorp N, Fossati M, Rostaing P, Triller A and Charrier C, Unique properties of dually innervated dendritic spines in pyramidal neurons of the somatosensory cortex uncovered by 3D correlative light and electron microscopy (2021) Plos Biology. 19(8) : e3001375.
Fossati M, Charrier C, Trans-synaptic interactions of ionotropic glutamate receptors (2020) Curr Opin Neurobiol, 66:85-92.
Fossati M, Assendorp N, Gemin O, Colasse S, Dingli F, Arras G, Loew D and Charrier C, Tans-synaptic signaling via the glutamate receptor delta-1 mediates inhibitory synapse formation in cortical pyramidal neurons (2019) Neuron, 104(6):1081-1094.e7.
Maffei A, Charrier C, Caiati M, Barberis A, Mahadevan V, Woodin M and Tyagarajan SK, Emerging mechanisms underlying dynamics of GABAergic synapses (2017) J Neurosci. 37(45) : 10792–10799.
Fossati M, Pizzarelli R, Schmidt ER, Kupferman JV, Stroebel D, Polleux F, Charrier C, SRGAP2 and its human-specific paralog co-regulate the development of excitatory and inhibitory synapses (2016) Neuron, 91(2):356-69.
Charrier C and Polleux F, How human-specific SRGAP2 gene duplications control human brain development (2012) Médecine/Sciences, 28(11):911-4.
Charrier C, Joshi K, Coutinho-Budd J, Kim JE, Lambert N, de Marchena J, Jin WL, Vanderhaeghen P, Ghosh A, Sassa T and Polleux F, Inhibition of SRGAP2 by its human-specific paralogs induces neoteny during spine maturation (2012) Cell, 149(4):923-35.
