Alice Lebreton
Group leader, INRAE research director
Research in my group explores the dynamics of Listeria monocytogenes intracellular lifestyles and of the molecular dialogue engaged with its host cell. We keep a strong focus on understanding the mechanisms of gene expression regulation in infected cells and their consequences.
| Group Bacterial infection, response & dynamics Institute of Biology of École normale supérieure (IBENS) UMR CNRS 8197, Inserm 1024 46 rue d’Ulm F – 75005 Paris |
e-mail Tel: +33 1 44 32 34 62 Fax: +33 1 44 32 39 41 |
Research career
| Since 2015 | Group leader, IBENS, INRAE Research director since 2022, HDR. “Post-transcriptional regulation of host gene expression in response to infection by intracellular bacteria.” |
| 2008-2014 | INRA Research scientist, Pasteur Institute (lab P. Cossart, group H. Bierne), Paris. “Chromatin subversion & regulation of host gene expression by Listeria monocytogenes.” |
| 2006-2008 | Post-doctoral fellow, Centre de Génétique Moléculaire (lab B. Séraphin), CNRS, Gif-sur-Yvette. “RNA exosome activity and nuclear RNA quality control in eukaryotes.” |
| 2002-2006 | PhD student, Pasteur Institute (lab A. Jacquier, supervision M. Fromont-Racine), Paris. “Dynamics of ribosome biogenesis in the yeast Saccharomyces cerevisiae.” |
| 2000 | Intern, Microbiology Institute (lab Th. Leisinger), ETH Zürich. “Transformation of isopropylamine to L-alaninol by Pseudomonas.” |
| 1999 | Summer intern, La Pitié-Salpêtrière hospital, Paris. “Histology of a murine model for Parkinson Disease.” |
Teaching
| Since 2023 | Professor in the biology department of École normale supérieure. In charge of the IMaLiS Master’s degree. |
| Since 2015 | Co-organisation of the Microbial Systems course (IMaLiS Master’s degree). |
| Since 2014 | Lecturer for the biology department of ENS. Courses: Molecular Cell Biology; Functional Genomics (Bachelor’s degree). |
| Since 2011 | Lecturer at ENS Paris-Saclay for the Cell Biology of Host-Invasive Bacteria Interactions course (Master’s degree) and Great discoveries in Life Sciences course (Bachelor’s degree). |
| 2019-2022 | Jury for the biology entrance exam of École normale supérieure. |
| 2014-2018 | Organisation of the Molecular Cell Biology course for non-biologist ENS students (Bachelor’s degree) from 2014 to 2018. |
| 2017-2018 | Responsible for the Fundamental Biology for Heath curriculum (ENS IMaLiS Master’s degree). |
| 2002-2005 | Teaching assistant in Immunology (Bachelor’s degree), Paris 7 University. |
Diffusion
| Since 2018 | Chronicles in biology in Le Monde. |
| Since 2014 | Broad audience escape game in epidemiology in scientific festivals; conferences after Sci-Fi movies; broad audience conferences on cellular hijacking by Listeria; radio emissions. |
| And... | a few other experiments. |
Education
| 2002-2006 | PhD in Microbiology-Virology, Paris 7 University. |
| 1998-2002 | Studies in Biochemistry and Cell Biology at École normale supérieure de Cachan (now ENS Paris-Saclay) and Paris 7 University. Undergraduate studies in Biochemistry and Cell Biology, then Master’s degree in Microbiology-Virology (Pasteur Institute). Agrégation (French degree for high-school teaching) in Biochemistry – Biological Engineering. |
