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Publications of the team

Gonzalez, R. and Félix, M.-A. (2023). Natural monobacterial environments modulate viral infection in Caenorhabditis elegans. bioRxiv Link

Frézal, L.*, Saglio, M.*, Zhang, G., Noble, L., Richaud, A. and Félix, M.-A. (2023). Genome-wide association and environmental suppression of the mortal germline phenotype of wild C. elegans. EMBO Reports, e58116. Link

Dubois, C. and Félix, M.-A. (2023). A QTL on chromosome IV explains a natural variation of QR.pap final position in Caenorhabditis elegans. Link

Schild, E.S., Gupta, S., Dubois, C., Fernandes Póvoa, E.E., Félix M.-A., Mugler, A., Korswagen, H.C. (2023). Precise temporal control of neuroblast migration through combined regulation and feedback of a Wnt receptor. Link

Tandonnet S, Haq M, Turner A, Grana T, Paganopoulou P, Adams S, Dhawan S, Kanzaki N, Nuez I, Félix MA, Pires-daSilva A. (2023). De novo genome assembly of Auanema melissensis, a trioecious free-living nematode. Link

Tran TD, Ali MA, Lee D, Félix MA, Luallen RJ. (2022). Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host. Link

Grover M, Fasseas MK, Essmann C, Liu K, Braendle C, Félix MA, Glockling SL, Barkoulas M. (2021). Infection of C. elegans by Haptoglossa species reveals shared features in the host response to oomycete detection. Link

Morgan E, Longares JF, Félix MA, Luallen RJ. (2021). Selective cleaning of wild Caenorhabditis nematodes to enrich for intestinal microbiome bacteria. Link

Zhang, F.*, Weckhors, J.L.*, Assié, A., Hosea, A.C., Ayoub, C.A., Khodakova, A.S., Loeza Cabrera, M., Vidal Vilchis, D., Félix, M.-A., Samuel, B.S. (2021). Natural genetic variation drives microbiome selection in the Caenorhabditis elegans gut. Link

Lee, D.*, Zdraljevic, S.* Stevens, L. Wang, Y. Tanny, R.E., Crobie, T.A., Cook, D.E., Webster, A.K., Chirakar, R., Baugh, L.R., Sterken, M.G., Braendle, C., Félix, M.-A., Rockman, M.V., Andersen, E.A. (2021). Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. Link

Félix, M.-A. (2021). Evolution : Drivers in a traffic jam. Link

Dubois, C.*, Gupta, S.*, Mugler, A.# and Félix M.-A.# (2021). Temporally regulated cell migration is sensitive to body size. Link
The people behind the papers – Clément Dubois, Shivam Gupta, Andrew Mugler and Marie-Anne Félix. Link

Félix, M.-A. (2020). "Hérédité" dans L’identité - Dictionnaire Encyclopédique. Sous la direction de Jean Gayon. Editions Gallimard. Collection Folio Essais. ISBN : 978-2-07-283413-4.

Besnard, F.*#, Picao Osorio, J.*, Dubois, C., and Félix, M.-A.# (2020). A broad mutational target explains a fast rate of phenotypic evolution. Link

Launay, C., Félix, M.-A., Dieng, J. and Delattre, M. (2020). Diversification and hybrid incompatibility in auto-pseudogamous species of Mesorhabditis nematodes. Link

Dirksen, P.*, Assié, A.*, Zimmermann, J., Zhang, F., Tietje, A.-M., Arnaud Marsh, A., Félix, M.-A., Shapira, M., Kaleta, C., Schulenburg, H.# and Samuel, B.S.# (2020). CeMbio - The C. elegans microbiome resource. Link

Beets, I., Zhang, G., Fenk, L., Chen, C., Nelson, G.M., Félix, M.-A.# and de Bono, M.# (2020). Natural variation in a dendritic scaffold protein modifies experience-dependent plasticity by altering neuropeptide expression. Link

Richaud, A., Frézal, L., Tahan, S., Zhao, G., Kaur, T., Wang, D.# and Félix, M.-A.# (2019). Vertical transmission in Caenorhabditis nematodes of RNA molecules encoding a viral RNA-dependent RNA polymerase. Link

Lee, D., Zdraljevic, S., Cook, D.E., Frézal, L., Hsu, J.-C., Sterken, M.G., Riksen, J.A.G., Wang, J., Kammenga, J.E., Braendle, C., Félix, M.-A., Schroeder, F.C. and Andersen, E.C. (2019). Selection and gene flow shape niche-associated variation in pheromone response. Link

Frézal, L., Jung, H., Tahan, S. Wang, D. and Félix, M.-A. (2019). Noda-like RNA viruses infecting Caenorhabditis nematodes : sympatry, diversity and reassortment. Link

Félix, M.-A.# and Wang, D. Natural viruses of Caenorhabditis. (2019). Link

Grosmaire, M.*, Launay, C.*, Siegwald, M., Brugière, T., Estrada-Virrueta, L., Berger, D., Burny, C., Modolo, L., Blaxter, M., Meister, P., Félix, M.-A., Gouyon, P.-H., Delattre, M. (2019). Males as somatic investment in a parthenogenetic nematode. Link

Stevens, L., Félix, M.-A., Beltran, T., Braendle, C., Caurcel, C., Fausett, C., Fitch, D.H.A., Frézal, L., Kaur, T., Kiontke, K.C., Newton, M.D., Noble, L.M., Richaud, A., Rockman, M.V., Sudhaus, W. Blaxter, M. (2019). Comparative genomics of ten new Caenorhabditis species. Link

Page, A.P., Roberts, M., Félix, M.-A., Pickard, D., Page, A., Weir, W. (2019). The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes. Link

Vargas-Velazquez, A.M., Besnard, F. and Félix, M.-A. (2019). Necessity and contingency in developmental genetic screens : LIN-3, Wnt and semaphorin pathways in vulval induction of the nematode Oscheius tipulae. Link

Grimbert, S., Vargas Velazquez, A.M., Braendle, C. (2018). Physiological starvation promotes Caenorhabditis elegans vulval induction. Link

Félix, M.-A., Ailion, M., Hsu, J.-C., Richaud, A. and Wang, J. (2018). Pristionchus nematodes occur frequently in diverse rotting vegetal substrates and are not exclusively necromenic, while Panagrellus redivivoides is found specifically in rotting fruits. Link

Frézal, L., Demoinet, E., Braendle, C., Miska, E# and Félix, M.-A.# (2018). Natural genetic variation in a multigenerational phenotype in C. elegans. Link

Osman, G.A.*, Fasseas, M.K.*, Koneru, S.L., Essmann, C.L., Kyrou, K., Srinivasan, M.A., Zhang, G., Sarkies, P., Félix, M.-A and Barkoulas, M. (2018). Natural infection of C. elegans by an oomycete reveals a new pathogen-specific immune response. Link

Richaud, A., Zhang, G., Lee, D. Lee, J. and Félix, M-A. (2018). The local co-existence pattern of selfing genotypes in Caenorhabditis elegans natural metapopulations. Link

Besnard, F.*, Koutsovoulos, G.*, Dieudonné, S., Blaxter, M.# and Félix, M.-A.# (2017). Towards universal forward genetics : using a draft genome sequence of the nematode Oscheius tipulae to identify mutations affecting vulva development. Link

Schulenburg, H., and Félix, M.-A. (2017). The natural biotic environment of C. elegans. Link

Zhang, F.*, Berg, M.*, Dierking, K., Félix, M.-A., Shapira, M.#, Samuel, B.# and Schulenburg, H.# (2017). Caenorhabditis elegans as a model for microbiome research. Link

Nigon, V.M. and Félix, M.-A. (2017) History of research on C. elegans and other free-living nematodes as model organisms. Wormbook, The C. elegans research Community, ed. Link

Zhang, G., Sachse, M., Prevost, M.-C., Luallen, R.J., Troemel, E. and Félix, M.-A. (2016). A large collection of novel nematode-infecting microsporidia and their diverse interactions with Caenorhabditis elegans and other related nematodes. Link

Barkoulas, M.*#, Vargas Velazquez, A.M*, Peluffo, A.E. and Félix, M.-A.# (2016). Evolution of new cis-regulatory motifs required for cell-specific gene expression in Caenorhabditis. Link

Cook, D.C., Zdraljevic, S., Tanny, R.E., Seo, B., Riccardi, D.D., Noble, L.M., Rockman, M.V., Alkema, M.J., Braendle, C., Kammenga, J.E., Wang, J., Kruglyak, L., Félix, M-A., Lee, J., Andersen, E.C. (2016). The genetic basis of natural variation in C. elegans telomere length. Link

Grimbert, S., Tietze, K., Barkoulas, M., Sternberg, P.W., Félix, M.-A. and Braendle, C. (2016). Anchor cell signaling anf vulval precursor cell positioning establish a reproducible spatial context during C. elegans vulval induction. Link

Luallen, R.J., Reinke, A.W., Tong, L., Botts, M.R., Félix, M.-A. and Troemel, E.R. (2016). Discovery of a natural microsporidian pathogen with a broad tissue tropism in Caenorhabditis elegans. Link

Samuel, B.S., Rowedder, H., Braendle, C., Félix, M.-A.* and Ruvkun, G.* (2016). Caenorhabditis elegans responses to bacteria from its natural habitats. Link

Dirksen, P., Arnaud Marsh, S., Braker, I., Heitland, N., Wagner, S., Nakad, R., Mader, S., Petersen, C., Kowallik, V., Rosenstiel, P., Félix, M-A. and Schulenburg, H. (2016). The native microbiome of the nematode Caenorhabditis elegans : Gateway to a new host-microbiome model. Link

Félix, M.-A. (2016). Phenotypic evolution with and beyond genome evolution. Link

Félix, M.-A. and Barkoulas, M. (2015). Pervasive robustness in biological systems. Link

Frézal, L. and Félix, M.-A. (2015). C. elegans outside the Petri dish. Link

McGill, L.M., Shannon, A.J., Pisani, D., Félix, M.-A., Ramløv, H., Dix, I., Wharton, D.A. and Burnell, A.M. (2015). Anhydrobiosis and freezing-tolerance : adaptations that facilitate the establishment of Panagrolaimus nematodes in polar habitats. Link

Barrière, A. and Félix, M.-A. (2014). Isolation of C. elegans and related nematodes. Wormbook, The C. elegans Research Community, ed. Link

Félix, M.-A., Braendle, C., Cutter, A.D. (2014). A streamlined system for species diagnosis in Caenorhabditis (Nematoda : Rhabditidae) with name designations for 15 distinct biological species. Link

Franz, C., Renshaw, H., Frézal, L., Jiang, Y., Félix, M.-A., Wang, D. (2014). Orsay, Santeuil and Le Blanc viruses primarily infect intestinal cells in Caenorhabditis nematodes. Link

Hodgkin, J., Félix, M.-A., Clark, L.C., Stroud, D., Gravato-Nobre, M.J. (2013). Two Leucobacter strains exert complementary virulence on Caenorhabditis including death by worm-star formation. Link

Ashe, A.*, Bélicard, T.*, Le Pen, J.*, Sarkies, P.*, Frézal, L., Lehrbach, N.J., Félix, M.-A.# and Miska, E.A.# (2013). A deletion polymorphism in the C. elegans RIG-I homolog disables viral RNA dicing and antiviral immunity. Link

Félix, M.-A.*, Jovelin, R.*, Ferrari, C., Han, S., Cho, Y.R., Andersen, E.C., Cutter, A.D., Braendle, C. (2013). Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest. Link

Barkoulas, M., van Zon, J.S., Milloz, J., van Oudenaarden, A., Félix, M.-A. (2013). Robustness and epistasis in the C. elegans vulval signalling network revealed by pathway dosage modulation. Link

Félix, M.-A. (2012). Evolution in developmental phenotype space. Link

Franz, C., Zhao, G., Félix, M.-A., Wang, D. (2012). Complete genome sequence of Le Blanc virus, a third Caenorhabditis nematode infecting virus. Link

Félix, M.-A. (2012). Caenorhabditis elegans vulval cell fate patterning. Link

Bélicard, T. and Félix, M.-A. (2012). Transmission multigénérationnelle de l’interférence à l’ARN chez le nématode C. elegans. Link

Félix, M.-A. and Duveau, F. (2012). Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C. briggsae. Link

Félix, M.-A. and Barkoulas, M. (2012). Robustness and flexibility in nematode vulva development. Link

Gerke, J.P.*, Andersen, A.C.*, Shapiro J.A.*, Crissman, J.R., Ghosh, R., Bloom, J.S., Félix, M.-A. and Kruglyak, L. (2012). Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity. Link

Nuez, I. and Félix M.-A. (2012). Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes. Link

Duveau, F. and Félix, M.-A. (2012). Role of pleiotropy in the evolution of a cryptic developmental variation in C. elegans. Link

Kiontke, K.*, Félix, M.-A.*, Ailion, M., Rockman, M.V., Braendle, C., Pénigault, J.-B. and Fitch, D.H.A. (2011). A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruits. Link

Pénigault, J.-B. and Félix, M.-A. (2011). Evolution of a system sensitive to stochastic noise : P3.p cell fate in Caenorhabditis. Link

Pénigault, J.-B. and Félix, M.-A. (2011). High sensitivity of C. elegans vulval precursor cells to the dose of posterior Wnts. Link

Hoyos, E.*, Kim, K.*, Milloz, J., Barkoulas, M., Pénigault, J.-B., Munro, E. and Félix, M.-A. (2011). Quantitative variation in autocrine signaling and pathway crosstalk in the Caenorhabdidtis vulva network. Link

Félix, M.-A.*#, Ashe, A.*, Piffaretti, P.*, Wu, G., Nuez, I., Bélicard, T. , Jiang, Y., Zhao, G., Franz, C.J., Goldstein, L.D., Sanroman, M., Miska, E.A.# and Wang, D.# (2011). Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses. Link

Félix, M.-A. and Braendle, C. (2010). The natural history of Caenorhabditis elegans. Link

Woodruff, G.C., Eke, O., Baird, S.E., Félix, M.-A. and Haag, E.S. (2010). Insights into species divergence and the evolution of hermaphroditism from fertile interspecies hybrids of Caenorhabditis nematodes. Link

Duveau, F. and Félix, M.-A. (2010). Hidden variation mapped. Link

Braendle, C., Baer, C. and Félix, M.-A. (2010). Evolution of the mutationally accessible phenotypic space in a developmental system. Link

Cutter, A.D., Yan, W., Tsvetkov, N., Sunil, S. and Félix, M.-A. (2010). Molecular population genetics and phenotypic sensitivity to ethanol for a globally diverse sample of the nematode Caenorhabditis briggsae. Link

Raboin, M.J., Timko, A.F., Howe, D.K., Félix, M.-A., and Denver, D.R. (2010). Evolution of Caenorhabditis mitochondrial genome pseudogenes and C. briggsae natural isolates. Link

Félix, M.-A. (2009). Variations génétiques et environnementales dans un réseau de signalisation intercellulaire. Link

Braendle, C. and Félix, M.-A. (2009). New fashion models. Link

Delattre, M. and Félix, M.A. (2009). The evolutionary context of robust and redundant cell biological mechanisms. Link

Braendle, C. and Félix, M.-A. (2009). The other side of phenotypic plasticity : a developmental system that generates an invariant phenotype despite environmental variation. Link

Troemel, E.R., Félix, M.-A., Whiteman, N.K., Barrière, A. and Ausubel, F.M. (2008). Microsporidia are natural intracellular parasites of the nematode C. elegans. Link

Félix, M.-A. (2008). RNA interference in nematodes and the chance that favored Sydney Brenner. Link

Braendle, C. and Félix, M.-A. (2008). Plasticity and errors of a robust developmental system in different environments. Link

Milloz, J., Duveau, F., Nuez, I. and Félix, M.-A. (2008). Intraspecific evolution of the intercellular signaling network underlying a robust developmental system. Link

Félix, M.-A. (2008). Q&A : Marie-Anne Félix. Link

Baïlle, D., Barrière, A. and Félix, M.-A. (2008). Oscheius tipulae, a widespread hermaphroditic soil nematode, displays a higher genetic diversity and geographic structure than Caenorhabditis elegans. Link

Dolgin, E.S. Félix, M.-A. and Cutter, A.D. (2008). Hakuna Nematoda : Genetic and phenotypic diversity in African isolates of Caenorhabditis elegans and C. briggsae. Link

Braendle, C., Milloz, J. and Félix, M.-A. (2008). Mechanisms and evolution of environmental responses in Caenorhabditis elegans. Link

Félix, M.-A. and Wagner, A. (2008). Robustness and evolution : concepts, insights, and challenges from a developmental model system. Link

Kiontke, K., Barrière, A., Kolotuev, I., Podbilewicz, B., Sommer, R., Fitch, D.H.A. and Félix, M.-A. (2007). Evolution of development in the nematode vulva system : trends, stasis and drift. Link

Winter, A.D., Keskiaho, K., Kukkola, L., McCormack, G., Félix, M.-A., Myllyharju, J. and Page, A.P. (2007). Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits. Link

Barrière, A. and Félix, M.-A. (2007). Temporal dynamics and linkage disequilibrium in natural C. elegans populations. Link

Félix, M.-A. (2007). Cryptic quantitative evolution of the vulva intercellular network in Caenorhabditis. Link

Félix, M.-A. (2006). Oscheius tipulae. Wormbook, The C. elegans research Community, ed. Link

Cutter, A.D., Félix, M.-A., Barrière, A. and Charlesworth, D. (2006). Patterns of nucleotide polymorphism distinguish temperate and tropical wild isolates of Caenorhabditis briggsae. Link

Braendle, C. and Félix, M.-A. (2006). Sex determination : Ways to evolve a hermaphodite. Link

Flatt, T. and Braendle, V. (2006). A role for genetic accommodation in evolution ? Link

Barrière, A. and Félix, M.-A. (2006). Isolation of C. elegans and related nematodes. Wormbook, The C. elegans research Community, ed. Link

Barrière, A. and Félix, M.-A. (2005). Natural variation and population genetics of Caenorhabditis elegans. Wormbook, The C. elegans research Community, ed. Link

Barrière, A. and Félix, M.-A. (2005). High local genetic diversity and low outcrossing rate in Caenorhabditis elegans natural populations. Link

Maupas, E. (1900), English translation by Félix, M.-A. (2005). Modes and forms of reproduction of nematodes. Wormbase. Link pdf

( Félix, M.-A. (2005). An inversion in the wiring of an intercellular signal : evolution of Wnt signaling in the nematode vulva.) see Note Link

Félix, M.-A. and Barrière, A. (2005). Evolvability of cell specification mechanisms. Link

Dichtel-Danjoy, M.-L. and Félix, M.-A. (2004). Phenotypic neighborhood and micro-evolvability. Link

Félix, M.-A. (2004). Alternative morphs and plasticity of vulval development in a rhabditid nematode species. Link

Félix, M.-A. (2003). Développement et systématique chez les nématodes (Ordre Rhabditida). Biosystema 21.

Félix, M.-A. (2004). Genomes : a helpful cousin for our favourite worm. Link

Dichtel-Danjoy, M.-L. and Félix, M.-A. (2004). The two steps of vulval induction in Oscheius tipulae CEW1 recruit common regulators including a MEK kinase. Link

Félix, M.-A. (2004). Developmental biology of nematodes - what we learn from Caenorhabditis elegans. In Nematology advances and perspectives : nematode management and utilization. Z.X. Chen, S.Y. Chen, D.W. Dickson, Eds. CABI Publishing, vol. I, pp. 71-174.

Bonnaud, L., Delattre, M. and Félix, M.-A. (2004). Division and fate of vulval precursor cells : is polymorphism an image of interspecific divergence ? Nematology Monographs & Perspectives, vol. 2, 691-694.

Louvet-Vallée, S., Kolotuev, I., Podbilewicz, B. and Félix, M.-A. (2003). Control of vulval competence and centering in the nematode Oscheius sp. 1 CEW1. Link

Félix, M.-A., Labouesse, M. and Ségalat, L. (2002) Caenorhabditis elegans, un organisme modèle pour la biologie. Editions Hermann, Paris. 200 pp.

Delattre, M. and Félix, M.-A. (2001). Microevolutionary studies in nematodes : a beginning. Link

Félix, M.-A., Vierstraete, A. and Vanfleteren, J. (2001). Three biological species related to Rhabditis (Oscheius) pseudodolichura Körner in Osche, 1952. Link

Delattre, M. and Félix, M.-A. (2001). Polymorphism and evolution of vulval precursor cell lineages within two nematode genera, Caenorhabditis and Oscheius. Link

Delattre, M. and Félix, M.-A. (2001). Evolution and development of a variable left-right asymmetry in nematodes : the handedness of P11/P12 migration. Link

Dichtel, M.-L.*, Louvet-Vallée, S.*, Viney, M.E.*, Félix, M.-A., Sternberg, P.W. (2001). Control of vulval cell division number in the nematode Oscheius/Dolichorhabditis sp. CEW1. Link

Félix, M.-A., De Ley, P., Sommer, R.J., Frisse, L., Nadler, S.A., Thomas, W.K., Vanfleteren, J. and Sternberg, P.W. (2000). Evolution of vulva development in the Cephalobina (Nematoda). Link

Félix, M.-A., Delattre, M. and Dichtel, M.-L. (2000). Comparative developmental studies using Oscheius / Dolichorhabditis sp. CEW1 (Rhabditidae). Link

Delattre, M. and Félix, M.-A. (1999). Connection of vulval and uterine epithelia in Caenorhabditis elegans. Link

Louvet-Vallée, S. and Félix, M.-A. (1999). Le lien entre reproduction et longévité... chez C. elegans. Link

De Ley, P., Félix, M.-A., Frisse, L. M., Nadler, S. A., Sternberg, P. W. and Thomas, W. K. (1999). Molecular and morphological characterisation of two reproductively isolated species with mirror-image anatomy (Nematoda : Cephalobidae). Link

Félix, M.-A. (1999). Evolution of developmental mechanisms in nematodes. Link